Atrizin 10mg Tablet | ePharma
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Atrizin 10mg Tablet

Generic: Cetirizine Hydrochloride

Type: Tablet

Pack Size: 10 Pcs

Cetirizine Hydrochloride is used in adults and in children (aged 6 years or above) to treat symptoms associated with:

  • Allergic rhinitis (such as nasal congestion, itchy nose, repeated sneezing, and red, watery, and itchy eyes)
  • Chronic Idiopathic Urticaria (severe skin rash with reddish raised patches and itching)

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✅ Description:

Atrizin 10mg Tablet is a medication that contains the active ingredient cetirizine, which is classified as an anti-allergic medicine. It is primarily used to relieve symptoms associated with allergic rhinitis (such as nasal congestion, itchy nose, repeated sneezing, and red, watery, and/or itchy eyes) and urticaria (a skin condition characterized by reddish raised patches on the skin with severe itching). This medication can be taken by both adults and children aged 6 years and above.

It is important to take Atrizin 10mg Tablet exactly as directed by your physician. The preferred time for administration is in the evenings or at bedtime, and it can be taken with or without meals. Before starting this medication, you should inform your doctor if you have any liver or kidney problems. It is also important to let your doctor know if you have epilepsy or difficulties with urination.

Atrizin 10mg Tablet is not recommended for use in patients with severe kidney impairment. In pregnant or breastfeeding women, it should only be used if the potential benefits outweigh the risks and if it is considered necessary by the physician.

One of the common side effects of Atrizin 10mg Tablet is excessive drowsiness and tiredness. Therefore, it is advised to refrain from engaging in activities that require complete concentration, such as driving or operating heavy machinery, as a precaution.

Other frequently reported side effects of taking Atrizin 10mg Tablet include dryness of the mouth, headache, tiredness, weakness, and sore throat. If these side effects trouble you, it is advisable to consult your doctor for further guidance.

Safety Advices


Alcohol
UNSAFE

Avoid consumption of alcohol while taking Atrizin 10mg Tablet as it might make you feel dizzier and drowsier.


Pregnancy
CONSULT YOUR DOCTOR

It is recommended not to take the Atrizin 10mg Tablet unless it is advised by your doctor. Inform your doctor if you are pregnant or think you may be pregnant.


Breastfeeding
CONSULT YOUR DOCTOR

Atrizin 10mg Tablet passes into breast milk; therefore, it is advised not to take this medicine while breastfeeding, unless it is prescribed by your doctor.


Driving
CAUTION

Atrizin 10mg Tablet is known to cause sleepiness and dizziness. If you experience these symptoms you should avoid driving.


Kidney
CAUTION

Atrizin 10mg Tablet is to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.


Liver
CAUTION

Atrizin 10mg Tablet should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.

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✔️ Uses of Atrizin 10mg Tablet
  • Common Allergies,
  • Hay Fever
  • Conjunctivitis
  • Eczema
  • Reactions to insect bites and stings
  • skin rashes.
  • Utricaria
  • Blocked Or Runny Nose
  • Sneezing
✔️ How does Atrizin 10mg Tablet work?

Atrizin 10mg Tablet is an anti-allergic medicine. It reduces allergic reactions by blocking the release of certain chemicals (histamines) in the body that triggers the allergic response. As a result, it provides relief from the symptoms of allergic rhinitis and urticaria.

✔️ Side Effects of Atrizin 10mg Tablet
  • Tiredness
  • Headache
  • Sleepiness, drowsiness
  • Nausea
  • Dizziness
  • Swelling and irritation inside the nose (rhinitis)
  • Dry mouth
  • Sore throat
✔️ Quick Suggestions:
  • Atrizin 10mg Tablet helps relieve allergy symptoms such as itching, swelling, and rashes.
  • It generally has few drug interactions and can be taken with most other medications. However, it's always advisable to consult your doctor or pharmacist before taking any new medications.
  • Caution should be exercised while driving or engaging in activities that require concentration, as Atrizin 10mg Tablet can cause dizziness and sleepiness.
  • Staying hydrated is important, especially for individuals with a cough or cold. Drinking liquids at room temperature can help alleviate cough, runny nose, and sneezing.
  • Stress can affect the immune system and increase the risk of getting sick. Regular exercise, meditation, deep breathing, and progressive muscle relaxation techniques can help relieve stress.
  • Adequate sleep is essential for overall health and well-being. It is recommended to aim for 7-9 hours of sleep each night.
  • Avoiding contact with known allergens, such as pollen and dust, is advised. Additionally, if certain food items are known to cause allergies, it is best to avoid them.
  • Personal hygiene should be maintained, and surroundings should be kept clean to minimize exposure to allergens and potential triggers.
  • It is important to avoid consuming alcohol while taking Atrizin 10mg Tablet, as it can increase sleepiness.
  • If you have an upcoming allergy test, it is recommended to stop taking Atrizin 10mg Tablet at least three days prior to the test, as it may affect the test results.
✔️ Indication

Atrizin 10mg Tablet is an anti-allergic medicine used to provide relief from various allergic conditions characterised by a runny or blocked nose, watery eyes, fever, rash, sinus and the common cold.

✔️ Pharmacology

Cetirizine hydrochloride is a potent H1 receptor antagonist that effectively blocks the effects of histamine. Unlike other antihistamines, it does not have significant anticholinergic or antiserotonergic effects. At therapeutic doses, cetirizine has minimal sedative effects and does not cause behavior changes.

When a dose of 10 mg cetirizine is administered, it reaches peak plasma concentration within approximately 1 hour, with levels of 257 mcg/L in adults and 980 mcg/L in children. Food intake does not affect the extent of absorption, although it may slightly delay the absorption process. The peak blood concentration of approximately 0.3 μg/ml is reached 30 to 60 minutes after taking a 10 mg dose of cetirizine.

The plasma half-life of cetirizine is around 11 hours, meaning it takes approximately 11 hours for half of the drug to be eliminated from the bloodstream. The absorption rate of cetirizine from one individual to another is consistent and predictable. Renal clearance, which represents the rate at which the drug is removed from the body by the kidneys, is approximately 30 ml/min. The excretion half-life, which indicates the time it takes for half of the drug to be eliminated from the body, is approximately 9 hours.

It's important to note that the pharmacokinetics of cetirizine can vary slightly among individuals, and the information provided here represents general characteristics of the drug's absorption, distribution, metabolism, and elimination. Specific dosing instructions and considerations should be followed as directed by a healthcare professional.

✔️ Dosage & Administration of Atrizin 10mg Tablet

Adult Dose:

  • For allergic conditions, the usual adult dose is 10 mg once daily or 5 mg twice daily.
  • Elderly patients or those with hepatic impairment should start with 5 mg once daily.

Child Dose:

  • For allergic conditions, the recommended doses are as follows:
    • Children aged 6-23 months: 2.5 mg once daily, which can be increased to a maximum of 2.5 mg twice daily in children older than 12 months.
    • Children aged 2-5 years: 5 mg once daily or in 2 divided doses.
    • For children aged 6 years and above 10 mg once daily or in 2 divided doses.
  • The safe and efficacy of cetirizine in children under 6 years of age have not been established.

Renal Dose:

  • In patients with renal impairment:
    • If the glomerular filtration rate (GFR) is greater than 50 mL/min, no dose adjustment is necessary.
    • If the GFR is 50 mL/min or less, the recommended dose is 5 mg once daily.
    • For patients undergoing peritoneal dialysis, the recommended dose is 5 mg once daily.
    • For patients undergoing intermittent hemodialysis, the recommended dose is 5 mg once daily, or it can also be administered three times weekly.

Administration:

  • Cetirizine may be taken with or without food.

It's important to note that dosages may vary depending on the specific condition being treated and individual patient factors. Always follow the dosage instructions provided by your healthcare provider.

✔️ Interaction

Atrizin 10mg Tablet can interact with several medications and substances. Here are the known interactions:

  • Pain killer (antipyrine): There may be a potential interaction between Atrizin 10mg Tablet and antipyrine, although the specific details of the interaction are not mentioned. It is advisable to consult with a healthcare professional or pharmacist before combining these medications.
  • Antibiotics (azithromycin, erythromycin): There are no specific interactions mentioned between Atrizin 10mg Tablet and azithromycin or erythromycin. However, it is always recommended to consult with a healthcare professional or pharmacist before combining medications.
  • Antacid (cimetidine): Cimetidine may increase the blood levels of cetirizine, the active ingredient in Atrizin 10mg Tablet. This can potentially increase the risk of side effects. It is advisable to consult with a healthcare professional before combining these medications.
  • Anti-fungal (ketoconazole): Ketoconazole may increase the blood levels of cetirizine, which can potentially increase the risk of side effects. It is advisable to consult with a healthcare professional before combining these medications.
  • Respiratory disease medicine (theophylline): Theophylline and cetirizine can potentially have additive effects on the central nervous system, leading to increased sedation or other side effects. Close monitoring is recommended if these medications are used together.
  • Decongestant (pseudoephedrine): Pseudoephedrine can potentially increase blood pressure and heart rate, and combining it with cetirizine may increase the risk of these effects. Caution is advised when using these medications together.
  • Anti-viral or anti-HIV drugs (ritonavir): Ritonavir may increase the blood levels of cetirizine, which can increase the risk of side effects. Close monitoring is recommended if these medications are used together.
  • Regarding drug-food interactions:
  • Alcohol: It is advised to avoid alcohol while taking Atrizin 10mg Tablet, as it may increase the risk of excessive drowsiness or other side effects.
  • St. John's wort plant: There is no specific interaction mentioned, but St. John's wort can potentially interact with various medications. It is advisable to consult with a healthcare professional before combining it with Atrizin 10mg Tablet.

Regarding drug-disease interactions:

  • Kidney disease: Atrizin 10mg Tablet is contraindicated in patients with severe kidney impairment.
  • Epilepsy (fits): Atrizin 10mg Tablet is contraindicated in patients with epilepsy or a history of seizures.
  • Urinary bladder problem: Atrizin 10mg Tablet is contraindicated in patients with difficulty in passing urine or urinary bladder problems.
  • Alcoholism: Atrizin 10mg Tablet is contraindicated in individuals with alcoholism.
✔️ Contraindications

Patients who have a history of allergy to cetirizine or hydroxyzine are contraindicated.

✔️ Pregnancy & Lactation

According to the United States FDA classification, cetirizine hydrochloride is categorized as pregnancy classification B. This classification indicates that there are no adequate and well-controlled studies on pregnant women. While animal studies have not shown any adverse effects on fetal development, it is important to note that animal studies do not always accurately predict the human response.

Therefore, the use of cetirizine hydrochloride during pregnancy should only be considered if the potential benefits outweigh the potential risks and only when clearly necessary. It is advisable to consult with a healthcare professional before taking cetirizine or any medication during pregnancy.

Cetirizine hydrochloride has been shown to be excreted in human milk. Therefore, caution should be exercised when administering cetirizine to lactating women. It is recommended to consult with a healthcare professional before using cetirizine while breastfeeding to assess the potential risks and benefits for both the mother and the infant.

It is always important to discuss any concerns or questions regarding medication use during pregnancy or while breastfeeding with a healthcare professional who can provide personalized advice based on the individual's specific situation.

✔️ Precautions & Warnings

Pregnancy and breast-feeding: Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Atrizin 10mg Tablet should be used during pregnancy or breastfeeding only if considered necessary by your doctor. It is important to discuss the potential risks and benefits with your healthcare provider.

Kidney problems: If you have kidney problems, your doctor may need to adjust the dose of Atrizin 10mg Tablet based on the severity of your condition. It is important to inform your doctor about your kidney problems before starting the medication.

Difficulty passing urine and epilepsy: Inform your doctor if you have difficulty passing urine or epilepsy (fits) before starting Atrizin 10mg Tablet. These conditions may require special precautions or dose adjustments.

Skin testing: If you are scheduled to undergo skin testing, your doctor may advise you to stop taking Atrizin 10mg Tablet 72 hours before the test. Atrizin 10mg Tablet can decrease the response to skin prick tests, so it is important to follow your doctor's instructions.

Mental alertness and activities: Patients should be cautious when engaging in activities that require mental alertness, such as operating machinery or driving a motor vehicle, after taking Atrizin 10mg Tablet. The medication can cause drowsiness and reduce mental alertness.

Alcohol and antidepressants: Concurrent use of Atrizin 10mg Tablet with alcohol or other antidepressants should be avoided. Combining these substances can further decrease mental alertness and increase the risk of side effects.

Overdosage: It is important to avoid taking an overdose of Atrizin 10mg Tablet. Higher doses can increase the risk of sleepiness and drowsiness. Always follow the recommended dosage instructions provided by your healthcare provider.

✔️ Storage Conditions

Keep in a dry place away from light and heat. Keep out of the reach of children.

Frequently Asked Questions (FAQ)

Yes

Depending upon the severity of allergic conditions due to allergens Atrizin 10mg Tablet can be safely taken daily until you get complete relief and as long as your doctor has advised you to take it

Yes

Atrizin 10mg Tablet should be used in children and adolescents (aged 6 years or above) only if prescribed by the physician. It is not recommended for use in children aged below 6 years. Therefore, consult your doctor for advice.

You may notice improvement in your condition within 1-2 hours following the administration of Atrizin 10mg Tablet. However, it may take few days for Atrizin 10mg Tablet to reduce the onset of allergic response.

Atrizin 10mg Tablet is an anti-allergic medication, not a steroid

Atrizin 10mg Tablet is preferably taken during bedtime after food. However, you may also take Atrizin 10mg Tablet in the mornings if advised by your doctor.
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Check our pricing section for Atrizin 10mg Tablet price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Pricing Information, Availability:
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